diff --git a/Content.Server/GameTicking/Rules/AntagLoadProfileRuleSystem.cs b/Content.Server/GameTicking/Rules/AntagLoadProfileRuleSystem.cs
index b93904c685..3527e2a11c 100644
--- a/Content.Server/GameTicking/Rules/AntagLoadProfileRuleSystem.cs
+++ b/Content.Server/GameTicking/Rules/AntagLoadProfileRuleSystem.cs
@@ -31,16 +31,18 @@ public sealed class AntagLoadProfileRuleSystem : GameRuleSystem<AntagLoadProfile
             ? _prefs.GetPreferences(args.Session.UserId).SelectedCharacter as HumanoidCharacterProfile
             : HumanoidCharacterProfile.RandomWithSpecies();
 
-        SpeciesPrototype? species;
-        if (ent.Comp.SpeciesOverride != null)
-        {
-            species = _proto.Index(ent.Comp.SpeciesOverride.Value);
-        }
-        else if (profile?.Species is not { } speciesId || !_proto.TryIndex(speciesId, out species))
+
+        if (profile?.Species is not { } speciesId || !_proto.TryIndex(speciesId, out var species))
         {
             species = _proto.Index<SpeciesPrototype>(SharedHumanoidAppearanceSystem.DefaultSpecies);
         }
 
+        if (ent.Comp.SpeciesOverride != null
+            && (ent.Comp.SpeciesOverrideBlacklist?.Contains(new ProtoId<SpeciesPrototype>(species.ID)) ?? false))
+        {
+            species = _proto.Index(ent.Comp.SpeciesOverride.Value);
+        }
+
         args.Entity = Spawn(species.Prototype);
         _humanoid.LoadProfile(args.Entity.Value, profile?.WithSpecies(species.ID));
     }
diff --git a/Content.Server/GameTicking/Rules/Components/AntagLoadProfileRuleCOmponent.cs b/Content.Server/GameTicking/Rules/Components/AntagLoadProfileRuleCOmponent.cs
index 0816902ad4..3a4cb5fc75 100644
--- a/Content.Server/GameTicking/Rules/Components/AntagLoadProfileRuleCOmponent.cs
+++ b/Content.Server/GameTicking/Rules/Components/AntagLoadProfileRuleCOmponent.cs
@@ -10,8 +10,14 @@ namespace Content.Server.GameTicking.Rules.Components;
 public sealed partial class AntagLoadProfileRuleComponent : Component
 {
     /// <summary>
-    /// If specified, the profile loaded will be made into this species.
+    /// If specified, the profile loaded will be made into this species if the chosen species matches the blacklist.
     /// </summary>
     [DataField]
     public ProtoId<SpeciesPrototype>? SpeciesOverride;
+
+    /// <summary>
+    /// List of species that trigger the override
+    /// </summary>
+    [DataField]
+    public HashSet<ProtoId<SpeciesPrototype>>? SpeciesOverrideBlacklist;
 }
diff --git a/Resources/Prototypes/GameRules/roundstart.yml b/Resources/Prototypes/GameRules/roundstart.yml
index da198a25d0..d5cd6a3f97 100644
--- a/Resources/Prototypes/GameRules/roundstart.yml
+++ b/Resources/Prototypes/GameRules/roundstart.yml
@@ -82,6 +82,11 @@
   - type: AntagSelection
   - type: AntagLoadProfileRule
     speciesOverride: Human
+    speciesOverrideBlacklist:
+    #Species that do not work with nukies should be included in this list.
+    #Once the issues are fixed the species should be removed from this list to be enabled.
+    #Balance concerns are not a valid reason to disable a species, except for high-impact Nukie-specific exploits.
+    - Vox
 
 - type: entity
   parent: BaseNukeopsRule