diff --git a/Resources/Prototypes/Reagents/medicine.yml b/Resources/Prototypes/Reagents/medicine.yml
index 6937b20dd1..26ca6fa266 100644
--- a/Resources/Prototypes/Reagents/medicine.yml
+++ b/Resources/Prototypes/Reagents/medicine.yml
@@ -124,7 +124,7 @@
           types:
             Radiation: -3
           groups:
-            Brute: 0.5
+            Brute: 1.5
 
 - type: reagent
   id: Bicaridine
@@ -560,14 +560,29 @@
         min: 4
   metabolisms:
     Medicine:
+      metabolismRate: 0.1
       effects:
       - !type:HealthChange
         damage:
           types:
-            Cellular: -1
-            Radiation: 1
-      - !type:ChemVomit
-        probability: 0.05
+            Cellular: -0.3
+            Radiation: 0.15
+            Caustic: 0.15
+      - !type:HealthChange
+        conditions:
+        - !type:ReagentThreshold
+          min: 11
+        damage:
+          types:
+            Radiation: 0.2
+      - !type:HealthChange
+        conditions:
+        - !type:ReagentThreshold
+          reagent: Arithrazine
+          min: 1
+        damage:
+          types:
+            Caustic: 0.3
 
 - type: reagent
   id: PolypyryliumOligomers
@@ -973,6 +988,21 @@
         - !type:ReagentThreshold
           min: 30
         probability: 0.02
+      - !type:ChemVomit
+        conditions:
+        - !type:ReagentThreshold
+          reagent: Arithrazine
+          min: 1
+        probability: 0.1
+      - !type:PopupMessage
+        conditions:
+        - !type:ReagentThreshold
+          reagent: Arithrazine
+          min: 1
+        type: Local
+        visualType: Medium
+        messages: [ "generic-reagent-effect-nauseous" ]
+        probability: 0.2
 
 - type: reagent
   id: Lacerinol